Computational biology

Postdoctoral researcher · Banfield Lab · UC Berkeley

Jacob West-Roberts

I work on microbes, massive datasets, and the kind of proteins that make structure predictors nervous.

I build computational systems for metagenomics, protein structure, comparative genomics, and AI-assisted biological research.

Fig. 1 · Predicted protein structure loading
Loading coordinates
Residues
2,000
Mean pLDDT
88.1
Model
Protenix
Rotation
32.1°
Cα trace of one segment of an unusually large protein. Drag to rotate.

Selected work

Five projects

  1. 01 Sharur Metagenomic research system Pre-release
  2. 02 Giant proteins Omnitrophota Preprint · 2023
  3. 03 Talea Sequence → geometry Public on GitHub
  4. 04 ELSA Genome context Public on GitHub
  5. 05 Gaia Protein search Science Advances · 2025

Selected papers

All papers →

  1. 2025 Gaia: An AI-enabled genomic context–aware platform for protein sequence annotation Science Advances · Co-first author
  2. 2023 Giant genes are rare but implicated in cell wall degradation by predatory bacteria bioRxiv · First author
  3. 2021 The Chloroflexi supergroup is metabolically diverse and representatives have novel genes for non-photosynthesis based CO2 fixation bioRxiv · First author